GSK0660
货号：
15272-50mg 基本售价：
7616.0 元 规格：
50 mg
产品信息
概述| 货号 | 15272-50mg |
| 描述 | GSK0660 is the first reported antagonist of PPARβ/δ (IC50 = 155 nM) with no measurable affinity for PPARα or PPARγ (IC50s ≥ 10 μM).1 Because of the limited bioavailability of GSK0660, the related compound GSK3787 (Item No. 15219) was developed as a selective PPARβ/δ antagonist with more suitable pharmacokinetic properties.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Shearer, B.G.,Steger, D.J.,Way, J.M., et al. Identification and characterization of a selective peroxisome proliferator-activated receptor b/d (NR1C2) antagonist. Molecular Endocrinology 22(2), 523-529 (2008).
2.Palkar, P.S.,Borland, M.G.,Naruhn, S., et al. Cellular and pharmacological selectivity of the peroxisome proliferator-activated receptor-β/δ antagonist GSK3787. Molecular Pharmacology 78(3), 419-430 (2010).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 418.5 |
| 分子式 | C19H18N2O5S |
| CAS号 | 1014691-61-2 |
| 稳定性 | ≥ 2 years |
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