货号 | 3896/50 |
别名 | (6S)-5,6,7,8-Tetrahydro-6-[propyl[2 |
供应商 | Tocris |
生物活性 | Dopamine D2 and D3 receptor agonist. Ki values are 13 and 0.71 nM for D2 and D3 respectively. Also has significant affinity for 5-HT1A and adrenergic α2B receptors. Exhibits antiparkinsonian acitivity. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 351.93 |
分子式 | C19H25NOS.HCl |
可溶性/溶解性 | Soluble to 10 mM in water with gentle warming and to 100 mM in DMSO |
CAS号 | 125572-93-2 |
参考文献 | Schelleret al (2009) The in vitro receptor profile of rotigotine: a new agent for the treatment of Parkinson's disease. Naunyn.Schmiedebergs.Arch.Pharmacol. 379 73. PMID: 18704368. Belluzziet al (2004) N-0923, a selective dopamine D2 receptor agonist, is efficacious in rat and monkey models of Parkinson's disease. Mov.Disord. 9147. |