IHR 1 (50 MG)
货号：
5554/50 基本售价：
7515.2 元 规格：
50 mg
产品信息
概述| 货号 | 5554/50 |
| 别名 | N,N'-1,4-Phenylenebis[2,5-dichlorobenzamide] |
性能| 供应商 | Tocris |
| 生物活性 | Potent Smo antagonist (IC50 = 7.6 nM). Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Blocks Smo accumulation in primary cilium in vitro. Fluorescent analog IHR-Cy3 also available. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 454.13 |
| 分子式 | C20H12Cl4N2< |
| 可溶性/溶解性 | Soluble to 20 mM in DMSO with gentle warming |
| 参考文献 | Fanet al (2014) The Hedgehog pathway effector smoothened exhibits signaling competency in the absence of ciliary accumulation. Chem.Biol. 21 1680. PMID: 25484239. |
