| 货号 | 0513/50 |
| 别名 | 1-(2-Diphenylmethoxyethyl)-4-(3-phe |
| 供应商 | Tocris |
| 生物活性 | A very potent and selective inhibitor of dopamine uptake (IC50 for inhibition of [3H]-dopamine uptake in rat striatal synaptosomes is 1.8 nM). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >99 % |
| 计算分子量 | 485.5 |
| 分子式 | C28H32N2O.2HCl |
| 可溶性/溶解性 | Soluble to 10 mM in water with gentle warming |
| CAS号 | 67469-57-2 |
| 参考文献 | Do-Regoet al (1999) Evidence for the sequential formation of two complexes between an uptake inhibitor, GBR 12783 [1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl-2-propenyl)piperazine], and the neuronal transporter of dopamine. J.Neurochem. 72 396. PMID: 9886093. Giroset al (1992) Cloning, pharmacological characterization and chromosome assignment of the human dopamine transporter. Mol.Pharmacol. 42 383. PMID: 1406597. Vaugeoiset al (1992) In vivo labelling of the neuronal dopamine uptake complex in the mouse striatum by [3H]GBR 12783. Eur.J.Pharmacol. 210 77. PMID: 1350989. Bonnet and Constentin (1986) GBR 12783, a potent and selective inhibitor of dopamine uptake: biochemical studies in vivoandex vivo. Eur.J.Pharmacol. 121 199. PMID: 3754516. |