| 货号 | 0806/50 |
| 别名 | 1-(Aminomethyl)cyclohexaneacetic acid |
| 供应商 | Tocris |
| 生物活性 | Anticonvulsant with several possible mechanisms of action. Increases GABA in the brain and binds to a novel site associated with voltage-sensitive Ca2+ channels. Prevents neuronal death and is antinociceptive and anxiolytic. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 171.24 |
| 分子式 | C9H17NO2 |
| 可溶性/溶解性 | Soluble to 100 mM in water with gentle warming |
| CAS号 | 60142-96-3 |
| 参考文献 | Finket al (2000) Inhibition of Ca2+ influx by gabapentin and subsequent reduction of neurotransmitter release from rat neocortical slices. Br.J.Pharmacol. 130 900. PMID: 10864898. Timmermanet al (2000) A microdialysis study on the mechanism of action of gabapentin. Eur.J.Pharmacol. 398 53. PMID: 10856447. Tayloret al (1998) A summary of mechanistic hypotheses of gabapentin pharmacology. Epilepsy Res. 29 233. PMID: 9551785. Upton (1994) Mechanisms of action of new antiepileptic drugs: rational design and serendipitous findings. TiPS 15 456. PMID: 7886818. |