货号 | 1695/50 |
别名 | (±)-4-Amino-5-chloro-N-[1-[(3R*,4S*) |
供应商 | Tocris |
生物活性 | 5-HT4 receptor agonist and gastrokinetic agent. Stimulates intestinal acetylcholine release, possibly via 5-HT4 receptor-dependent and -independent mechanisms, leading to increased intestinal motility. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 465.95 |
分子式 | C23H29ClFN3O4 |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
CAS号 | 81098-60-4 |
参考文献 | Briejeret al (1993) Cisapride and a structural analogue, R 76,186, are 5-hydroxytryptamine4(5-HT4) receptor agonists on the guinea-pig colon ascendens. Naunyn Schmiedebergs Arch.Pharmacol. 347 464. PMID: 8321323. Taniyamaet al (1991) Cisapride stimulates motility of the intestine via the 5-hydroxytryptamine receptors. J.Pharmacol.Exp.Ther. 258 1098. PMID: 1890614. Schuurkeset al (1985) Motor-stimulating properties of cisapride on isolated gastrointestinal preparations of the guinea pig. J.Pharmacol.Exp.Ther. 234 775. PMID: 3897516. |