SR 49059
货号：
17972-25mg 基本售价：
7504.0 元 规格：
25 mg
产品信息
概述| 货号 | 17972-25mg |
| 描述 | SR 49059 is a selective, nonpeptide antagonist of the V1a subtype of the vasopressin receptor (Ki = 1.1-6.3 nM in human).1,2 It demonstrates ≥2 orders of magnitude lower affinity for V1b, V2, and oxytocin receptors and does not exhibit any intrinsic agonist activity.1 SR 49059 can inhibit arginine vasopressin-induced human platelet aggregation with an IC50 value of 3.7 nM.1 |
| 别名 | Relcovaptan; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Serradiel-Le Gal, C.,Wagnon, J.,Garcia, C., et al. Biochemical and pharmacological properties of SR 49059, a new, potent, nonpeptide antagonist of rat and human vasopressin V1a receptors. Journal of Clinical Investigation 92, 224-231 (1993).
2.Thibonnier, M.,Conarty, D.M.,Preston, J.A., et al. Molecular pharmacology of human vasopressin receptors. Vasopressin and Oxytocin 1, 251-276 (1998).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 620.5 |
| 分子式 | C28H27Cl2N3O7S |
| CAS号 | 150375-75-0 |
| 稳定性 | ≥ 2 years |
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