2,3-dinor Thromboxane B2-d9
货号：
10009584-100ug 基本售价：
7462.0 元 规格：
100 ug
产品信息
概述| 货号 | 10009584-100ug |
| 描述 | 2,3-dinor Thromboxane B2-d9 (2,3-dinor TXB2-d9) contains 9 deuterium atoms at the 15, 15, 16, 16, 17, 17, 18, 18, and 18 positions. It is intended for use as an internal standard for the quantification of 2,3-dinor TXB2 (Item No. 19050) by GC- or LC-mass spectrometry. TXB2 is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2.1 2,3-dinor TXB2 is an abundant urinary metabolite of TXB2 and can be used as a marker for in vivoTXA2synthesis.1,2,3 In healthy male volunteers, the median excretion of 2,3-dinor TXB2 is 10.3 ng/hour (138 pg/mg creatine).2 |
| 别名 | 2,3-dinor TXB2-d9; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Ciabattoni, G.,Pugliese, F.,Davi, G., et al. Fractional conversion of thromboxane B2 to urinary 11-dehydrothromboxane B2 in man. Biochimica et Biophysica Acta 992, 66-70 (1989).
2.Lawson, J.A.,Brash, A.R.,Doran, J., et al. Measurement of urinary 2,3-dinor-thromboxane B2 and thromboxane B2 using bonded-phase phenylboronic acid columns and capillary gas chromatography-negative-ion chemical ionization mass spectrometry. Analytical Biochemistry 150, 463-470 (1985).
3.Lawson, J.A.,Patrono, C.,Ciabattoni, G., et al. Long-lived enzymatic metabolites of thromboxane B2 in the human circulation. Analytical Biochemistry 155, 198-205 (1986).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥99% deuterated forms (d1-d9) |
| 计算分子量 | 351.5 |
| 分子式 | C18H21D9O6 |
| 稳定性 | ≥ 1 year |
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