| 货号 | 3695/50 |
| 别名 | (RS)-2-Chloro-5-hydroxyphenylglycin |
| 供应商 | Tocris |
| 生物活性 | Sodium salt of the selective mGlu5 agonist CHPG (Cat. No. 1049). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 223.59 |
| 分子式 | C8H7ClNNaO3 |
| 可溶性/溶解性 | Soluble to 50 mM in water and to 50 mM in DMSO |
| 参考文献 | Baoet al (2001) Selective mGluR5 receptor antagonist or agonist provides neuroprotection in a rat model of focal cerebral ischaemia. Brain Res. 922 173. PMID: 11743947. Saltet al (1999) Antagonism of the mGlu5 agonist 2-chloro-5-hydroxyphenylglycine by the novel selective mGlu5 antagonist 6-methyl-2-(phenylethynyl)-pyridine (MPEP) in the thalamus. Br.J.Pharmacol. 127 1057. PMID: 10455248. Dohertyet al (1997) (RS)-2-Chloro-5-hydroxyphenylglycine (CHPG) activates mGlu5, but not mGlu1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus. Neuropharmacology 36 265. PMID: 9144665. |