DMXAA
货号：
2804-25 基本售价：
7399.5 元 规格：
25mg
产品信息
概述| 货号 | 2804-25 |
| 描述 | DMXAA acts as a tumor vascular disrupting agent, inducing apoptosis in tumor vascular endothelium resulting in necrosis at the tumor core. It potently activates the TANK-binding kinase 1-interferon regulatory factor 3 signaling pathway in leukocytes, inducing type-I-interferon production. In addition, DMXAA significantly inhibits several kinases in endothelial cells, including the vascular endothelial growth factor (VEGF) receptors VEGFR1 and VEGFR2 (IC₅₀ = 119 and 11 µM, respectively). Recent studies have shown that DMXAA is a competitive agonist ligand for mouse. |
性能| 供应商 | Biovision |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 外观 | White solid |
