货号 | 0881/50 |
别名 | 5-(2-Chloroethyl)-4-methylthiazole hydrochloride |
供应商 | Tocris |
生物活性 | Sedative and anticonvulsant which is neuroprotective in a number of animal models. Prevents the degeneration of serotonergic nerve terminals induced by MDMA ('Ecstasy'). |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 198.11 |
分子式 | C6H8ClNS.HCl |
可溶性/溶解性 | Soluble to 100 mM in water |
CAS号 | 533-45-9 |
参考文献 | Crosset al (1995) The protective action of chloromethiazole against ischaemia induced neurodegeneration in gerbils when infused at doses having little sedative or anticonvulsant activity. Br.J.Pharmacol. 114 1625. PMID: 7599932. Hewitt and Green (1994) Chloromethiazole, dizocilpine and haloperidol prevent the degeneration of serotonergic nerve terminals induced by the administration of MDMA ('Ecstasy') to rats. Neuropharmacology 33 1589. PMID: 7539115. |