BPIQ-I
货号：
17224-5mg 基本售价：
7350.0 元 规格：
5 mg
产品信息
概述| 货号 | 17224-5mg |
| 描述 | BPIQ-I is a quinazoline that inhibits the tyrosine kinase activity of the epidermal growth factor receptor (IC50 = 0.025 nM).1 It can inhibit the growth of SKOV3 and MDA-468 tumor cell lines with EC50 values of 6.5 and 30 µM, respectively.2 |
| 别名 | PD 159121; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Rewcastle, G.W.,Palmer, B.D.,Bridges, A.J., et al. Tyrosine kinase inhibitors. 9. Synthesis and evaluation of fused tricyclic quinazoline analogues as ATP site inhibitors of the tyrosine kinase activity of the epidermal growth factor receptor. Journal of Medicinal Chemistry 39(4), 918-928 (1996).
2.Rae, J.M., and Lippman, M.E. Evaluation of novel epidermal growth factor receptor tyrosine kinase inhibitors. Breast Cancer Research and Treatment 83(2), 99-107 (2004).
|
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 354.2 |
| 分子式 | C16H12BrN5 |
| CAS号 | 174709-30-9 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
