| 货号 | 9001150-10mg |
| 描述 | Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Different quorum sensing molecules are produced at different times in bacterial population growth and have distinct cellular effects mediated through changes in gene expression.1,2 N-3-hydroxyoctanoyl-L-Homoserine lactone is a small diffusible signaling molecule secreted by various bacteria.3,4 This lactone can have activating or suppressing effects on gene expression and biofilm formation, respectively.5,6 N-3-hydroxyoctanoyl-L-Homoserine lactone is produced via lactonolysis from 3-oxooctanoyl-homoserine lactone, altering quorum sensing or contributing to quorum quenching.7 |
| 别名 | OH-C8-HSL; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Kristiansen, S.,Bjarnsholt, T.,Adeltoft, D., et al. The Pseudomonas aeruginosa autoinducer dodecanoyl-homoserine lactone inhibits the putrescine synthesis in human cells. Acta Pathologica, Microbiologica, et Immunologica Scandinavica 116, 361-371 (2008). 2.Huang, Y.L.,Ki, J.S.,Lee, O.O., et al. Evidence for the dynamics of acyl homoserine lactone and AHL-producing bacteria during subtidal biofilm formation. ISME Journal 1-9 (2008). 3.Flodgaard, L.R.,Dalgaard, P.,Andersen, J.B., et al. Nonbioluminescent strains of Photobacterium phosphoreum produce the cell-to-cell communication signal N-(3-hydroxyoctanoyl)homoserine lactone. Applied and Environmental Microbiology 71(4), 2113-2120 (2005). 4.Lumjiaktase, P.,Diggle, S.P.,Loprasert, S., et al. Quorum sensing regulates dpsA and the oxidative stress response in Burkholderia pseudomallei. Microbiology 152, 3651-3659 (2006). 5.Duerkop, B.A.,Herman, J.P.,Ulrich, R.L., et al. The Burkholderia mallei BmaR3-BmaI3 quorum-sensing system produces and responds to N-3-hydroxy-octanoyl homoserine lactone. Journal of Bacteriology 190(14), 5137-5141 (2008). 6.Gamage, A.M.,Shui, G.,Wenk, M.R., et al. N-Octanoylhomoserine lactone signalling mediated by the BpsI-BpsR quorum sensing system plays a major role in biofilm formation of Burkholderia pseudomallei. Microbiology 157, 1176-1186 (2011). 7.Chan, K.G.,Atkinson, S.,Mathee, K., et al. Characterization of N-acylhomoserine lactone-degrading bacteria associated with the Zingiber officinale (ginger) rhizosphere: Co-existence of quorum quenching and quorum sensing in Acinetobacter and Burkholderia. BMC Microbiology 11(51), 1-13 (2011). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 243.3 |
| 分子式 | C12H21NO4 |
| CAS号 | 192883-14-0 |
| 稳定性 | ≥ 2 years |
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