Omeprazole sulfone
货号：
18882-50mg 基本售价：
7280.0 元 规格：
50 mg
产品信息
概述| 货号 | 18882-50mg |
| 描述 | Omeprazole sulfone is the major metabolite of the gastric proton pump inhibitor, omeprazole (Item No. 14880). It is produced by cytochrome P450 (CYP)3A4 sulfoxidation of esomeprazole (Item No. 17326) and is found in plasma.1 Omeprazole sulfone has been shown to act as a reversible direct-acting and metabolism-dependent inhibitor of CYP2C19 in pooled human liver microsomes (IC50 = 18 µM).2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Äbelö, A.,Andersson, T.B.,Antonsson, M., et al. Stereoselective metabolism of omeprazole by human cytochrome P450 enzymes. Drug Metabolism and Disposition 28(8), 966-972 (2000).
2.Ogilvie, B.W.,Yerino, P.,Kazmi, F., et al. The proton pump inhibitor, omeprazole, but not lansoprazole or pantoprazole, is a metabolism-dependent inhibitor of CYP2C19: Implications for coadministration with clopidogrel. Drug Metabolism and Disposition 39(11), 2020-2033 (2011).
|
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 361.4 |
| 分子式 | C17H19N3O4S |
| CAS号 | 88546-55-8 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
