SR 2595
货号:
18291-10mg 基本售价:
7280.0 元 规格:
10 mg
产品信息
概述货号 | 18291-10mg |
描述 | SR 2595 is an inverse agonist of PPARγ (IC50 = 30 nM) that represses both transactivation in a promoter:reporter assay and expression of the adipogenic marker fatty acid-binding protein 4 in differentiating murine preadipocytes.1 Repression of PPARγ with SR 2595 promotes osteogenesis, as measured by calcium phosphatase deposition, in cultured human mesenchymal stem cells (MSCs).1 SR 2595 also increases expression of bone morphogenetic proteins BMP2 and BMP6 in MSCs.1 |
性能供应商 | Cayman |
应用文献 |
1.Marciano, D.P.,Kuruvilla, D.S.,Boregowda, S.V., et al. Pharmacological repression of PPARγ promotes osteogenesis. Nature Communications 6, 1-7 (2015).
|
运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 558.7 |
分子式 | C37H38N2O3 |
CAS号 | 1415252-61-7 |
稳定性 | ≥ 2 years |
声明本官网所有报价均为常温或者蓝冰运输价格,如有产品需要干冰运输,需另外加收干冰运输费。 |