BG45
货号：
16918-50mg 基本售价：
7280.0 元 规格：
50 mg
产品信息
概述| 货号 | 16918-50mg |
| 描述 | BG45 is an HDAC class I inhibitor with selectivity for HDAC3 (IC50 = 289 nM). It inhibits HDAC1, HDAC2, and HDAC6 with greatly reduced potency (IC50s = 2, 2.2, and >20 µM, respectively).1 At concentrations up to 50 mg/kg, BG45 alone or in combination with bortezomib has been shown to dose-dependently inhibit tumor growth in a mouse model of multiple myeloma.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Minami, J.,Suzuki, R.,Mazitschek, R., et al. Histone deacetylase 3 (HDAC3) as a novel therapeutic target in multiple myeloma. Leukemia 28(3), 680-689 (2014).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 214.2 |
| 分子式 | C11H10N4O |
| CAS号 | 926259-99-6 |
| 稳定性 | ≥ 2 years |
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