货号 | 14001-50mg |
描述 | Alliin is a cysteine sulfoxide constituent of garlic that is converted by alliinase to allicin, which imparts its pungent aroma and flavor.1,2 Alliin exhibits anti-cancer, anti-microbial, anti-hypertensive, cardioprotective, and anti-oxidant activities.3,4,5 It has been shown to inhibit squalene monooxygenase, a rate-limiting step in the downstream pathway of cholesterol biosynthesis, with an IC50 value of 120 μM.6,7 |
别名 | (±)-Allyl-L-cysteine sulfoxide; |
供应商 | Cayman |
应用文献 | |
1.Jones, M.G.,Collin, H.A.,Tregova, A., et al. The biochemical and physiological genesis of alliin in garlic. Intl.J.Biomed.Pharma.Sci. 1(1), 21-24 (2007). 2.Ohsumi, C.,Hayashi, T. and Sano, K. Formation of alliin in the culture tissues of Allium sativum. Oxidation of S-allyl-L-cysteine. Phytochemistry 33(1), 107-111 (1993). 3.Asdaq, S.M. and Inamdar, M.N. Potential of garlic and its active constituent, S-allyl cysteine, as antihypertensive and cardioprotective in presence of captopril. Phytomedicine 17(13), 1016-1026 (2010). 4.Kim, J.M.,Chang, H.J.,Kim, W.K., et al. Structure-activity relationship of neuroprotective and reactive oxygen species scavenging activities for allium organosulfur compounds. Journal of Agricultural and Food Chemistry 54, 6547-6553 (2006). 5.Louis, X.L.,Murphy, R.,Thandapilly, S.J., et al. Garlic extracts prevent oxidative stress, hypertrophy and apoptosis in cardiomyocytes: A role for nitric oxide and hydrogen sulfide. BMC Complement.Altern.Med. 12, (2012). 6.Bagiu, R.V.,Vlaicu, B. and Butnariu, M. Chemical composition and in vitro antifungal activity screening of the Allium ursinum L. (Liliaceae). International Journal of Molecular Sciences 13, 1426-1436 (2012). 7.Gupta, N. and Porter, T.D. Garlic and garlic-derived compounds inhibit human squalene monooxygenase. Journal of Nutrition 131, 1662-1667 (2001). | |
运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 177.2 |
分子式 | C6H11NO3S |
CAS号 | 17795-26-5 |
稳定性 | ≥ 2 years |
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