| 货号 | 11878-10mg |
| 描述 | Curcuminoids are natural and synthetic analogs of curcumin (Item No. 81025), a natural polyphenol with modulating effects in inflammation, cancer, and immunity.1 Salicylcurcumin is a synthetic curcuminoid which, like bisdemethoxycurcumin (Item No. 10960), lacks methoxy groups on both phenols. Furthermore, the hydroxyl groups on each phenol are positioned ortho, as in salicylates, rather than in the para position typical of curcuminoids. Salicylcurcumin has antioxidant and anticarcinogenic properties.2,3 Also, it increases the activity of quinone reductase in mouse hepatoma cells in a dose-dependent fashion, doubling activity at 0.3 μM salicylcurcumin.4,5 |
| 别名 | Salicylcurcuminoid; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Grynkiewicz, G., and Slifirski, P. Curcumin and curcuminoids in quest for medicinal status. Acta.Biochim.Pol. 59(2), 201-212 (2012). 2.Manju, M.,Sherin, T.G.,Rajasekharan, K.N., et al. Curcumin analogue inhibits lipid peroxidation in a freshwater teleost, Anabas testudineus (Bloch)--an in vitro and in vivo study. Fish Physiology and Biochemistry 35, 413-420 (2009). 3.Anto, R.J.,George, J.,Babu, K.V., et al. Antimutagenic and anticarcinogenic activity of natural and synthetic curcuminoids. Mutation Research 370, 127-131 (1996). 4.Dinkova-Kostova, A.T., and Talalay, P. Relation of structure of curcumin analogs to their potencies as inducers of Phase 2 detoxification enzymes. Carcinogenesis 20(5), 911-914 (1999). 5.Magesh, S.,Chen, Y., and Hu, L. Small molecule modulators of Keap1-Nrf2-ARE pathway as potential preventive and therapeutic agents. Medicinal Research Reviews 32(4), 687-726 (2012). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 308.3 |
| 分子式 | C19H16O4 |
| CAS号 | 1236545-54-2 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |