PGDM-d4
货号：
11344-100ug 基本售价：
7252.0 元 规格：
100 ug
产品信息
概述| 货号 | 11344-100ug |
| 描述 | Prostaglandin DM (PGDM)-d4 contains four deuterium atoms at the 18, 18, 19 and 19 positions. It is intended for use as an internal standard for the quantification of PGDM by GC- or LC-mass spectrometry. PGD2 plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle.1 PGDM is a major urinary metabolite of PGD2 with a unique lower sidechain that readily undergoes reversible cyclization.2 It is used as a biomarker to assess endogenous production of PGD2. |
| 别名 | Prostaglandin D Metabolite-d4; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Giles, H., and Leff, P. The biology and pharmacology of PGD2. Prostaglandins 35, 277-300 (1988).
2.Morrow, J.D.,Prakash, C.,Awad, J.A., et al. Quantification of the major urinary metabolite of prostaglandin D2 by a stable isotope dilution mass spectrometric assay. Analytical Biochemistry 193, 142-148 (1991).
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| 运输条件 | Dry ice in continental US; may vary elsewhere |
| 存放说明 | -80 |
| 纯度 | ≥99% deuterated forms (d1-d4) |
| 计算分子量 | 332.4 |
| 分子式 | C16H20D4O7 |
| 稳定性 | ≥ 6 months |
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