货号 | 0181/50 |
别名 | trans-4-Aminocrotonic acid |
供应商 | Tocris |
生物活性 | The trans-isomer of CACA. Potent GABAA agonist, GABA uptake inhibitor and substrate for GABA-T. Also GABAA-ρagonist. |
运输条件 | Blue Ice |
存放说明 | Ambient |
计算分子量 | 101.1 |
分子式 | C4H7NO2 |
可溶性/溶解性 | Soluble to 100 mM in water |
CAS号 | 38090-53-8 |
参考文献 | Chebibet al (1997) Analogues of γ-aminobutyric acid (GABA) and trans-4-aminocrotonic acid (TACA) substituted in the 2 position as GABAC receptor antagonists. Br.J.Pharmacol. 122 1551. PMID: 9422798. Johnstonet al (1996) GABAC receptors: relatively simple transmitter-gated ion channels. TiPS 17 319. PMID: 8885697. Johnstonet al(1975)cisandtrans-4-Aminocrotonic acid as GABA analogues of restricted conformation. J.Neurochem. 24 157. PMID: 234147. |