| 货号 | 1682/50 |
| 别名 | 2-(2-Pyridinyl)-(3H)-indol-3-one-1- |
| 供应商 | Tocris |
| 生物活性 | Purinergic P2Y receptor ligand. Displays irreversible antagonism at P2Y receptors in some smooth muscles but potentiates responses to ATP in other systems (chick brain recombinant P2Y1 receptor and sympathetic/purinergic nerve stimulation). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 396.42 |
| 分子式 | C13H8N2O2.C7H8O3S |
| 可溶性/溶解性 | Soluble to 15 mM in ethanol with gentle warming and to 80 mM in DMSO |
| CAS号 | 56583-49-4 |
| 参考文献 | Ren and Burnstock (1997) Prominent sympathetic purinergic vasoconstriction in the rabbit splenic artery: potentiation by 2.2'-pyridylisatogen tosylate. Br.J.Pharmacol. 120 530. PMID: 9031760. Kinget al (1996) Potentiation by 2,2'-pyridylisatogen tosylate of ATP-responses at a recombinant P2Y1 purinoceptor. Br.J.Pharmacol. 117 1111. PMID: 8882604. Speddinget al (1975) Antagonism of adenosine 5'-triphosphate-induced relaxation by 2-2'-pyridylisatogen in the taenia of guinea-pig caecum. Br.J.Pharmacol. 53 575. PMID: 1148500. |