IBC 293 (50 MG)
货号：
2469/50 基本售价：
7217.7 元 规格：
50 mg
产品信息
概述| 货号 | 2469/50 |
| 别名 | 1-(1-Methylethyl)-1H-benzotriazole-5-carboxylic acid |
性能| 供应商 | Tocris |
| 生物活性 | Highly selective agonist for GPR109B (HM74), human orphan G-protein-coupled receptor expressed in adipocytes. Selective for GPR109B over niacin receptor GPR109A (HM74A); EC50 values are 400 nM and > 1 μM respectively. Inhibits isoproterenol-stimulated lipolysis in vitro in isolated human adipocytes. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 205.22 |
| 分子式 | C10H11N3O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| CAS号 | 306935-41-1 |
| 参考文献 | Sempleet al (2006) 1-Alkyl-benzotriazole-5-carboxylic acids are highly selective agonists of the human orphan G-protein-coupled receptor GPR109b. J.Med.Chem. 49 1227. PMID: 16480258. |
