| 货号 | 1422/50 |
| 别名 | 5,6-Dichloro-1-ethyl-1,3-dihydro-2H |
| 供应商 | Tocris |
| 生物活性 | Stimulates Cl- secretion via the activation of hKCa3.1 (IK1) potassium channels and an apical Cl- conductance carried by the CFTR channel. More potent than its analog 1-EBIO (Cat. No. 1041). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 231.08 |
| 分子式 | C9H8Cl2N2O |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| CAS号 | 60563-36-2 |
| 参考文献 | Hamilton and Kiesslinget al (2006) DCEBIO stimulates Cl- secretion in the mouse jejunum. Am.J.Physiol.Cell Physiol. 290 152. PMID: 16135545. Singhet al (2001) Benzimidazolone activators of chloride secretion: potential therapeutics for cystic fibrosis and chronic obstructive pulmonary disease. J.Pharmacol.Exp.Ther. 296 600. PMID: 11160649. |