BRL 50481 (50 MG)
货号：
2237/50 基本售价：
7217.7 元 规格：
50 mg
产品信息
概述| 货号 | 2237/50 |
| 别名 | N,N,2-Trimethyl-5-nitro-benzenesulfonamide |
性能| 供应商 | Tocris |
| 生物活性 | Selective, substrate-competitive inhibitor of phosphodiesterase (PDE) 7 (Ki = 180 nM). Displays > 200-fold selectivity over PDE1B, PDE1C, PDE2, PDE3, PDE4A4 and PDE5. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 244.26 |
| 分子式 | C9H12N2O4S |
| 可溶性/溶解性 | Soluble to 100 mM in ethanol and to 100 mM in DMSO |
| CAS号 | 433695-36-4 |
| 参考文献 | Smithet al (2004) Discovery of BRL 50481 [3-(N,N-dimethylsulfonamido)-4-methyl-nitrobenzene], a selective inhibitor of phosphodiesterase 7: in vitro studies in human monocytes, lung macrophages, and CD8+ T-lymphocytes. Mol.Pharmacol. 66 1679. PMID: 15371556. |
