| 货号 | 19539-10mg |
| 描述 | Dehydro aripiprazole is the primary, active metabolite of aripiprazole, an atypical antipsychotic.1,2 The metabolite is produced from the parent compound by the actions of cytochrome P450 (CYP) isoforms CYP3A4 and CYP2D6.3 Dehydro aripiprazole has similar pharmacological properties to aripiprazole.4 |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Bauman, J.N.,Frederick, K.S.,Sawant, A., et al. Comparison of the bioactivation potential of the antidepressant and hepatotoxin nefazodone with aripiprazole, a structural analog and marketed drug. Drug Metabolism and Disposition 36(6), 1016-1029 (2008). 2.Kim, J.R.,Seo, H.B.,Cho, J.Y., et al. Population pharmacokinetic modelling of aripiprazole and its active metabolite, dehydroaripiprazole, in psychiatric patients. British Journal of Clinical Pharmacology 66(6), 802-810 (2008). 3.Spina, E. and de Leon, J. Metabolic drug interactions with newer antipsychotics: A comparative review. Basic & Clinical Pharmacology & Toxicology 100(1), 4-22 (2007). 4.Swainston Harrison, T. and Perry, C.M. Aripiprazole: A review of its use in schizophrenia and schizoaffective disorder. Drugs 64(15), 1715-1736 (2004). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 482.8 |
| 分子式 | C23H25Cl2N3O2 • HCl |
| CAS号 | 1008531-60-9 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |