| 货号 | 2662/50 |
| 别名 | 4-[2-Phenyl-5,7-bis(trifluoromethyl |
| 供应商 | Tocris |
| 生物活性 | Selective estrogen ERβ receptor antagonist that displays 36-fold selectivity over ERα. Exhibits full antagonism at ERβ in a cotransfection assay in human endometrial cancer cells (HEC-1), with minimal effects on ERα. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 423.31 |
| 分子式 | C20H11F6N3O |
| 可溶性/溶解性 | Soluble to 33 mM in DMSO and to 100 mM in ethanol |
| CAS号 | 805239-56-9 |
| 参考文献 | Comptonet al (2005) Erratum. J.Med.Chem. 482724. Comptonet al (2004) Pyrazolo[1,5-a]pyrimidines: estrogen receptor ligands possessing estrogen receptor β antagonist activity. J.Med.Chem. 47 5872. PMID: 15537344. |