| 货号 | 16369-100ug |
| 描述 | Docosahexaenoic acid (DHA; Item No. 90310) is an ω-3 fatty acid that is abundant in the brain and the retina and is known to be important in early development.1,2 Maresin 2 (MaR2) is a 13R,14S-dihydroxy DHA formed by recombinant human macrophage 12-lipoxygenase and soluble epoxide hydrolase co-incubated with DHA.3 At 1 ng/mouse, MaR2 was shown to reduce neutrophil infiltration by 40% in a mouse model of peritonitis, and at 10 pM, MaR2 can enhance human macrophage phagocytosis of zymosan A by 90%.3 Analytical and biological comparisons of synthetic MaR2 with endogenously derived MaR2 have confirmed its identity as matching the natural product.4 |
| 别名 | 13R,14S-diHDHA;13R,14S-dihydroxy Docosahexaenoic Acid;MaR2; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Su, H.M. Mechanisms of n-3 fatty acid-mediated development and maintenance of learning memory performance. Journal of Nutritional Biochemistry 21, 364-373 (2010). 2.Wu, T.C. and Chen, P.H. Health consequences of nutrition in childhood and early infancy. Pediatrics and Neonatology 50(4), 135-142 (2009). 3.Deng, B.,Wang, C.W.,Arnardottir, H.H., et al. Maresin biosynthesis and identification of maresin 2, a new anti-inflammatory and pro-resolving mediator from human macrophages. PLoS One 9(7), (2014). 4.Serhan, C. . (2007). | |
| 运输条件 | Dry ice in continental US; may vary elsewhere |
| 存放说明 | -80 |
| 纯度 | ≥95% |
| 计算分子量 | 360.5 |
| 分子式 | C22H32O4 |
| CAS号 | 1639809-46-3 |
| 稳定性 | ≥ 1 year |
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