Oxamflatin
货号：
13176-10mg 基本售价：
6944.0 元 规格：
10 mg
产品信息
概述| 货号 | 13176-10mg |
| 描述 | Oxamflatin is a potent inhibitor of histone deacetylases (IC50 = 15.7 nM).1 It has been shown to alter the expression of several genes whose products are involved in cell morphology, motility, apoptosis, and cell cycle control, reducing the proliferation of cancer cells.2,3,1 |
| 别名 | Metacept 3; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Kim, Y.B.,Lee, K.H.,Sugita, K., et al. Oxamflatin is a novel antitumor compound that inhibits mammalian histone deacetylase. Oncogene 18, 2461-2470 (1999).
2.Peart, M.J.,Tainton, K.M.,Ruefli, A.A., et al. Novel mechanisms of apoptosis induced by histone deacetylase inhibitors. Cancer Research 63, 4460-4471 (2003).
3.Dear, A.E., and Medcalf, R.L. The novel anti-tumour agent oxamflatin differentially regulates urokinase and plasminogen activator inhibitor type 2 expression and inhibits urokinase-mediated proteolytic activity. Biochimica et Biophysica Acta 1492, 15-22 (2000).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 342.4 |
| 分子式 | C17H14N2O4S |
| CAS号 | 151720-43-3 |
| 稳定性 | ≥ 2 years |
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