| 货号 | 19616-500ug |
| 描述 | Concanamycin C is a natural macrolide antibiotic first isolated from Streptomyces and identified as an inhibitor of T cell proliferation in response to concanavalin A (Item No. 14951).1,2 Concanamycin C is cytotoxic to fungi, including yeasts, through its ability to inhibit vacuolar-type ATPases.3,4 |
| 别名 | 4-O-de(aminocarbonyl)-Concanamycin A; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Kinashi, H.,Someno, K., and Sakahguchi, K. Isolation and characterization of concanamycins A, B and C. J. Antibiot. (Tokyo) 37(11), 1333-1343 (1984). 2.Dröse, S., and Altendorf, K. Bafilomycins and concanamycins as inhibitors of V-ATPases and P-ATPases. Journal of Experimental Biology 200, 1-8 (1997). 3.Bowman, E.J., and Bowman, B.J. Cellular role of the V-ATPase in Neurospora crassa: Analysis of mutants resistant to concanamycin or lacking the catalytic subunit A. J. Exp. Biol. 203(Pt 1), 97-106 (2000). 4.Bowman, E.J.,Graham, L.A.,Stevens, T.H., et al. The bafilomycin/concanamycin binding site in subunit c of the V-ATPases from Neurospora crassa and Saccharomyces cerevisiae. J. Biol. Chem. 279(32), 33131-33138 (2004). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 823.1 |
| 分子式 | C45H74O13 |
| CAS号 | 81552-34-3 |
| 稳定性 | ≥ 1 year |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |