| 货号 | 17864-5mg |
| 描述 | Hexa-N-acetylchitohexaose is a hexamer of N-acetylglucosamine, a subunit of the natural polymer chitin. It functions as an elicitor in plants, inducing the expression of chitinases.1,2 Like chitin and some of its derivatives, hexa-N-acetylchitohexaose is a substrate of lysozyme.3 It also binds LysM domains on certain proteins, including an endopeptidase of T. thermophilus.4 Hexa-N-acetylchitohexaose heightens the immune response against PseudomonasandListeria in mice, stimulates cytokine secretion in mesenchymal stem cells, and inhibits nitric oxide production by activated macrophages.5,6,7,8 |
| 别名 | N-Acetylchitohexaose;NACOS-6; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Inui, H.,Yamaguchi, Y., and Hirano, S. Elicitor actions of N-acetylchitooligosaccharides and laminarioligosaccharides for chitinase and L-phenylalanine ammonia-lyase induction in rice suspension culture. Bioscience, Biotechnology, and Biochemistry 61(6), 975-978 (1997). 2.Gao, Y.,Zan, X.L.,Wu, X.F., et al. Identification of fungus-responsive cis-acting element in the promoter of Brassica juncea chitinase gene, BjCHI1. Plant Science 215-216, 190-198 (2014). 3.Ouyang, Z.,Takáts, Z.,Blake, T.A., et al. Preparing protein microarrays by soft-landing of mass-selected ions. Science 301, 1351-1354 (2003). 4.Wong, J.E.M.M.,Midtgaard, S.R.,Gysel, K., et al. An intermolecular binding mechanism involving multiple LysM domains mediates carbohydrate recognition by an endopeptidase. Acta.Cryst. D71, 592-605 (2014). 5.Tokoro, A.,Kobayashi, M.,Tatewaki, N., et al. Protective effect of N-acetyl chitohexaose on Listeria monocytogenes infection in mice. Microbiology and Immunology 33(4), 357-367 (1989). 6.Okawa, Y.,Kobayashi, M.,Suzuki, S., et al. Comparative study of protetive effects of chitin, chitosan, and N-acetyl chitohexaose against Pseudomonas aeruginosa and Listeria monocytogenes infections in mice. Biological and Pharmaceutical Bullentin 26(6), 902-904 (2003). 7.Lieder, R.,Thormodsson, F.,Ng, C.H., et al. Chitosan and chitin hexamers affect expansion and differentiation of mesenchymal stem cells differently. Int.J.Biol.Macromol. 51(4), 675-680 (2012). 8.Hwang, S.M.,Chen, C.Y.,Chen, S.S., et al. Chitinous materials inhibit nitric oxide production by activated RAW 264.7 macrophages. Biochemical and Biophysical Research Communications 271(1), 229-233 (2000). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 1237.2 |
| 分子式 | C48H80N6O31 |
| CAS号 | 38854-46-5 |
| 稳定性 | ≥ 2 years |
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