LL-Z 1640-4
货号：
19159-5mg 基本售价：
6874.0 元 规格：
5 mg
产品信息
概述| 货号 | 19159-5mg |
| 描述 | LL-Z 1640-4 is a cis-enol resorcylic acid lactone that has been shown to exhibit both antiviral and antiprotozoan activity.1 While LL-Z 1640-4 is inactive against JNK/p38 kinase signaling, its companion antibiotic, (5Z)-7-oxo zeaenol (Item No. 17459), has been identified as an irreversible inhibitor of the MAPKKK, TAK1, blocking T cell activation.2 Thus, LL-Z 1640-4 is useful as negative control to help dissect the selectivity of this MAPKKK inhibitor. |
| 别名 | Antibiotic LLZ1640-4;(5Z)-Zeaenol;Curvularia Sp.; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Ellestad, G.A.,Lovell, F.M.,Perkinson, N.A., et al. New zearalenone related macrolides and isocoumarins from an unidentified fungus. The Journal of Organic Chemistry 43(12), 2339-2343 (1978).
2.Sellès, P., and Lett, R. Convergent stereospecific synthesis of LL-Z1640-2 (or C292), hypothemycin and related macrolides. Part 2. Tetrahedron Letters 43(26), 4627-4631 (2002).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥99% |
| 计算分子量 | 364.4 |
| 分子式 | C19H24O7 |
| CAS号 | 66018-41-5 |
| 稳定性 | ≥ 2 years |
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