货号 | 17890-25mg |
描述 | Naratriptan is a selective serotonin 5-HT1B agonist (pKi = 8.9 for human 5-HT1B) used in the treatment of severe cephalic pain, including migraine headaches.1,2,3 3,4-dihydro Naratriptan is an impurity formed during the preparation of naratriptan.4 |
别名 | Naratriptan Impurity B; |
供应商 | Cayman |
应用文献 | |
1.Gilmore, B. and Michael, M. Treatment of acute migraine headache. American Family Physician 83(3), 271-280 (2011). 2.Wurch, T.,Palmier, C.,Colpaert, F.C., et al. Recombinant saphenous vein 5-HT1B receptors of the rabbit: Comparative pharmacology with human 5-HT1B receptors. British Journal of Pharmacology 120(1), 153-159 (1997). 3.Ferrari, M.D.,Goadsby, P.J.,Roon, K.I., et al. Triptans (serotonin, 5-HT1B/1D agonists) in migraine: Detailed results and methods of meta-analysis of 53 trials. Cephalalgia 22, 633-658 (2002). 4.Kumar, U.S.,Sankar, V.R.,Kumar, S.B., et al. An investigation into formation of impurity B during the optimization of naratriptan hydrochloride. Organic Process Research & Development 13, 468-470 (2009). | |
运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 333.4 |
分子式 | C17H23N3O2S |
CAS号 | 121679-20-7 |
稳定性 | ≥ 2 years |
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