Tasquinimod
货号：
17692-25mg 基本售价：
6832.0 元 规格：
25 mg
产品信息
概述| 货号 | 17692-25mg |
| 描述 | Tasquinimod is an orally-active quinoline-3-carboxamide derived from roquinimex, an immunomodulatory quinolone with applications in some cancers and autoimmune diseases.1 Tasquinimod inhibits tumor angiogenesis and supplements radiation or chemotherapy in animal models of prostate cancer.1,2 While its precise mechanism of action remains unclear, tasquinimod has been reported to alter signaling through S100A9, thrombospondin-1, HIF-1α, androgen receptor, VEGF, and HDAC3/4.1,2 |
| 别名 | ABR-215050; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Isaacs, J.T. The long and winding road for the development of tasquinimod as an oral second-generation quinoline-3-carboxamide antiangiogenic drug for the treatment of prostate cancer. Expert Opinion on Investigational Drugs 19(10), 1235-1243 (2010).
2.Mehta, A.R. and Armstrong, A.J. Tasquinimod in the treatment of castrate-resistant prostate cancer - current status and future prospects. Ther.Adv.Urol. 8(1), 9-18 (2016).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 406.4 |
| 分子式 | C20H17F3N2O4 |
| CAS号 | 254964-60-8 |
| 稳定性 | ≥ 2 years |
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