| 货号 | 12069-25mg |
| 描述 | Astragaloside IV is a bioactive saponin first isolated from the dried plant roots of the genus Astragalus, which is used in traditional Chinese medicine.1 It dose-dependently inhibits human adenovirus type 3 (HAdV-3) in A549 cells (IC50 = 23 µM; LC50 = 865 µM).2 It inhibits replication of HAdV-3 and decreases HAdV-3-induced apoptosis. It has diverse protective effects for the cardiovascular, immune, digestive, and nervous systems.3,1 In particular, it reduces myocardial infarct size in dogs when administered prior to coronary ligation and reduces reperfusion arrhythmias in isolated rat hearts.4 |
| 别名 | AS-IV; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Ren, S.,Zhang, H.,Mu, Y., et al. Pharmacological effects of Astragaloside IV: A literature review. J.Tradit.Chin.Med. 33(3), 413-416 (2013). 2.Shang, L.,Qu, Z.,Sun, L., et al. Astragaloside IV inhibits adenovirus replication and apoptosis in A549 cells in vitro. J. Pharm. Pharmacol. 63(5), 688-694 (2011). 3.Li, L.,X., H.,Xu, R., et al. Research review on the pharmacological effects of astragaloside IV. Fundam. Clin. Pharmacol. 31(1), 17-36 (2017). 4.Zhang, W.-D.,Chen, H.,Zhang, C., et al. Astragaloside IV from Astragalus membranaceus shows cardioprotection during myocardial ischemia in vivo and in vitro. Planta Med. 72(1), 4-8 (2006). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 785 |
| 分子式 | C41H68O14 |
| CAS号 | 84687-43-4 |
| 稳定性 | ≥ 2 years |
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