Limaprost
货号：
13810-10mg 基本售价：
6832.0 元 规格：
10 mg
产品信息
概述| 货号 | 13810-10mg |
| 描述 | Limaprost is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is orally active in both rats and guinea pigs at doses of 100 µg/kg as an inhibitor of ADP and collagen induced platelet aggregation. Limaprost is 10-1,000 times more potent than PGE1 as an inhibitor of platelet adhesiveness measured in vitro. Intra-coronary injection (100 ng/kg) or intravenous injection (3 µg/kg) in anesthetized dogs causes vasodilation and increased coronary blood flow by 60-80%. Significant hypotensive effects were seen at 100 and 300 µg/kg orally in rats.1 |
| 别名 | 17α,20-dimethyl-Δ2-PGE1;17α,20-dimethyl-Δ2-Prostaglandin E1; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Tsuboi, T.,Hatano, N.,Nakatsuji, K., et al. Pharmacological evaluation of OP 1206, a prostaglandin E1 derivative, as an antianginal agent. Archives International Pharmacodynamics 247, 89-102 (1980).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 380.5 |
| 分子式 | C22H36O5 |
| CAS号 | 74397-12-9 |
| 稳定性 | ≥ 1 year |
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