VU 590 dihydrochloride (50 MG)
货号：
3891/50 基本售价：
6831.1 元 规格：
50 mg
产品信息
概述| 货号 | 3891/50 |
| 别名 | 7,13-Bis[(4-nitrophenyl)methyl]-1,4,10-trioxa-7,13-diazacyclopentadecane dihydrochloride |
性能| 供应商 | Tocris |
| 生物活性 | Inhibits the renal outer medullary potassium channel (Kir1.1, ROMK) (IC50 = 294 nM). Also inhibits the inward retifying K+ channel Kir7.1; displays no effect upon Kir2.1 or Kir4.1. Acts as an intracellular Kir1.1 channel pore blocker. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >97 % |
| 计算分子量 | 561.46 |
| 分子式 | C24H32N4O7.2HCl |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 313505-85-0 |
| 参考文献 | Lewiset al (2009) High-throughput screening reveals a small-molecule inhibitor of the renal outer medullary potassium channel and Kir7.1. Mol.Pharmacol. 76 1094. PMID: 19706730. |
