TRO 19622 (50 MG)
货号：
2906/50 基本售价：
6831.1 元 规格：
50 mg
产品信息
概述| 货号 | 2906/50 |
| 别名 | Cholest-4-en-3-one oxime; Olesoxime |
性能| 供应商 | Tocris |
| 生物活性 | Neuroprotective and neuroregenerative compound. Rescues motor neurons from axotomy-induced cell death and promotes nerve regeneration following sciatic nerve crush in vivo. Binds directly to two components of the mitochondrial permeability pore, the voltage-dependent anion channel (VDAC) and translocator protein; thought to inhibit MPTP opening. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 399.65 |
| 分子式 | C27H45NO |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO and to 20 mM in ethanol |
| CAS号 | 22033-87-0 |
| 参考文献 | Bordetet al (2007) Identification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis. J.Pharmacol.Exp.Ther. 322 709. PMID: 17496168. |
