| 货号 | 4401/50 |
| 别名 | 1-(3-Bromophenyl)-5-(2-furanylmethy |
| 供应商 | Tocris |
| 生物活性 | Inhibitor of formin homology 2 (FH2) domains. Prevents formin-mediated actin nucleation and barbed end elongation. Disrupts formin-dependent actin cytoskeletal structures in fission yeast and mammalian NIH 3T3 fibroblasts. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 377.21 |
| 分子式 | C15H9BrN2O3< |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Poinclouxet al (2011) Contractility of the cell rear drives invasion of breast tumor cells in 3D Matrigel. Proc.Natl.Acad.Sci.USA 108 1943. PMID: 21245302. Rizviet al (2009) Identification and characterization of a small molecule inhibitor of formin-mediated actin assembly. Chem.Biol. 16 1158. PMID: 19942139. |