S4 (50 MG)
货号：
5577/50 基本售价：
6831.1 元 规格：
50 mg
产品信息
概述| 货号 | 5577/50 |
| 别名 | 4-[[[(3,5-Dimethylphenyl)amino]carbonyl]amino]phenyl sulfamate |
性能| 供应商 | Tocris |
| 生物活性 | High affinity and selective CA IX and CA XII inhibitor (Ki values are 2, 7, 547 and 5600 nM for CA XII, IX, II andI, respectively). Inhibits migration and proliferation of breast cancer cells in vitro. Inhibits lung metastasis in mice bearing breast tumor xenografts, without affecting primary tumor. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 335.38 |
| 分子式 | C15H17N3O4 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 20 mM in ethanol |
| 参考文献 | Gielinget al (2012) Antimetastatic effect of sulfamate carbonic anhydrase IX inhibitors in breast carcinoma xenografts. J.Med.Chem. 55 5591. PMID: 22621623. |
