| 货号 | 2891/50 |
| 别名 | 1,2,3,9-Tetrahydro-9-methyl-3-[(2-m |
| 供应商 | Tocris |
| 生物活性 | Selective 5-HT3 receptor antagonist (Ki = 6.16 nM). Antiemetic; prevents emesis induced by cytotoxic drugs and radiation. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 329.83 |
| 分子式 | C18H19N3O.HCl |
| 可溶性/溶解性 | Soluble to 50 mM in water and to 100 mM in DMSO |
| 参考文献 | Ginawiet al (2005) Ondansetron, a selective antagonist, antagonizes methamphetamine-induced anorexia in mice. Pharmacol.Res. 51 255. PMID: 15661576. Yeet al (2001) Ondansetron: a selective 5-HT3 receptor antagonist and its applications in CNS-related disorders. CNS Drug Rev. 7 199. PMID: 11474424. Youssefyehet al (1992) Development of high-affinity 5-HT3 receptor antagonists. 1. Initial structure-activity relationship of novel benzamides. J.Med.Chem. 35 895. PMID: 1312602. |