NSC 405020 (50 MG)
货号：
4902/50 基本售价：
6831.1 元 规格：
50 mg
产品信息
概述| 货号 | 4902/50 |
| 别名 | 3,4-Dichloro-N-(1-methylbutyl)benzamide |
性能| 供应商 | Tocris |
| 生物活性 | Membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor (IC50 > 100 μmol/L). Directly interacts with the hemopexin domain (PEX) of MT1-MMP, affecting homodimerization and repressing its pro-tumorigenic activity in vivo. Displays no effect on the catalytic activity of MT1-MMP or MMP-2. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 260.16 |
| 分子式 | C12H15Cl2NO |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Remacleet al (2012) Novel MT1-MMP small-molecule inhibitors based on insights into hemopexin domain function in tumor growth. Cancer Res. 72 2339. PMID: 22406620. |
