货号 | 1436/50 |
别名 | (±)-N-[(1R*,2R*)-2-Phenylcyclopentyl |
供应商 | Tocris |
生物活性 | Inhibitor of adenylyl cyclase. Also inhibits cAMP and cGMP phosphodiesterases, and blocks slow extracellular and store-operated Ca2+ entry into cells. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >98 % |
计算分子量 | 377.01 |
分子式 | C23H36N2.HCl |
可溶性/溶解性 | Soluble to 20 mM in DMSO and to 20 mM in ethanol |
参考文献 | van Rossumet al (2000) Ca2+ entry mediated by store depletion, S-nitrosylation, and TRP3 channels. Comparison of coupling and function. J.Biol.Chem. 275 28562. PMID: 10878007. Hunt and Evans (1980) RMI 12330A, an inhibitor of cyclic nucleotide phosphodiesterases and adenylate cyclase in kidney preparations. Biochim.Biophys.Acta 613 499. PMID: 6256001. Guellaenet al (1977) RMI 12330 A, an inhibitor of adenylate cyclase in rat liver. Biochim.Biophys.Acta 484 465. PMID: 911855. |