货号 | 1944/50 |
别名 | 4-(8-Chloro-5,6-dihydro-11H-benzo[5 |
供应商 | Tocris |
生物活性 | Peripheral histamine H1 receptor antagonist (Ki = 35 nM); devoid of central effects. Orally active antiallergic agent. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 382.88 |
分子式 | C22H23ClN2O2 |
可溶性/溶解性 | Soluble to 25 mM in DMSO and to 100 mM in ethanol |
CAS号 | 79794-75-5 |
参考文献 | Kreutneret al (1987) Antiallergic activity of loratidine, a non-sedating antihistamine. Allergy 42 57. PMID: 2436504. Ahn and Barnett (1986) Selective displacement of [3H]mepyramine from peripheral vs. central nervous system receptors by loratadine, a non-sedating antihistamine. Eur.J.Pharmacol. 127 153. PMID: 2875889. Barnettet al (1984) Evaluation of the CNS properties of SCH 29851, a potential non-sedating antihistamine. Agents Actions 14 590. PMID: 6236679. |