| 货号 | 3144/50 |
| 别名 | 4,4'-[(2-Bromo-1,4-phenylene)di-(1E) |
| 供应商 | Tocris |
| 生物活性 | Potent amyloid fibril-specific fluorescent dye (EC50 = 20 - 30 nM). Exhibits minimal fluorescence in aqueous buffers and fluoresces brightly in the presence of Aβ,α-synuclein and tau in situ. (Optimum wavelength = 550 nm). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 393.27 |
| 分子式 | C22H17BrO2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| CAS号 | 872201-12-2 |
| 参考文献 | LeVine (2005) Mechanism of Aβ(1-40) fibril-induced fluorescence of (trans-trans)-1-bromo-2,5-bis(4-hydroxystyryl)benene (K114). Biochemistry 44 15937. PMID: 16313197. Crystalet al (2003) A comparison of amyloid fibrillogenesis using the novel fluorescent compound K114. J.Neurochem. 86 1359. PMID: 12950445. |