货号 | 0869/50 |
别名 | 2-Phenyl-1,3-propanedioldicarbamate |
供应商 | Tocris |
生物活性 | Anticonvulsant, acting as an antagonist at the NMDA-associated glycine binding site. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 238.24 |
分子式 | C11H14N2O4 |
可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
CAS号 | 25451-15-4 |
参考文献 | Coffinet al (1994) Selective antagonism of the anticonvulsant effects of felbamate by glycine. Eur.J.Pharmacol. 256 R9. PMID: 8050461. De Sarroet al (1994) Excitatory amino acid neurotransmission through both NMDA and non-NMDA receptors is involved in the anticonvulsant activity of felbamate in DBA/2 mice. Eur.J.Pharmacol. 262 11. PMID: 7529182. Serraet al (1994) Felbamate antagonises isoniazid- and FG7142-induced reduction of GABAA receptor function in the mouse brain. Eur.J.Pharmacol. 265 185. PMID: 7875235. Upton (1994) Mechanisms of action of new antiepileptic drugs: rational design and serendipitous findings. TiPS 15 456. PMID: 7886818. |