Ceranib 1 (50 MG)
货号：
4448/50 基本售价：
6831.1 元 规格：
50 mg
产品信息
概述| 货号 | 4448/50 |
| 别名 | 3-[(2E)-3-(4-Methoxyphenyl)-1-oxo-2-propen-1-yl]-6-methyl-4-phenyl-2(1H)-quinolinone |
性能| 供应商 | Tocris |
| 生物活性 | Ceramidase inhibitor; inhibits proliferation in SKOV3 ovarian carcinoma cells (IC50 = 3.9 μM). Induces accumulation of ceramide species and decreases sphingosine and sphingosine-1-phosphate (S1P) levels in SKOV3 cells. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 395.45 |
| 分子式 | C26H21NO3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Draperet al (2011) Discovery and evaluation of inhibitors of human ceramidase. Mol. Cancer Ther. 10 2052. PMID: 21885864. |
