C34 (50 MG)
货号：
5373/50 基本售价：
6831.1 元 规格：
50 mg
产品信息
概述| 货号 | 5373/50 |
| 别名 | 1-Methylethyl 2-(acetylamino)-2-deoxy-α-D-glucopyranoside 3,4,6-triacetate; TLR4-IN-C34 |
性能| 供应商 | Tocris |
| 生物活性 | TLR4 inhibitor; attenuates TLR4 signaling in enterocytes and macrophages in vitro, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis (NEC). Also suppresses LPS signaling in human ileum displaying NEC ex-vivo. Displays no significant effects on signaling via TLR2 or TLR9. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 389.4 |
| 分子式 | C17H27NO9 |
| 可溶性/溶解性 | Soluble to 50 mM in water and to 100 mM in DMSO |
| 参考文献 | Nealet al (2013) Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors. PLoS One 8 e65779. PMID: 23776545. |
