11-trans Leukotriene D4
货号：
20330-100ug 基本售价：
6748.0 元 规格：
100 ug
产品信息
概述| 货号 | 20330-100ug |
| 描述 | 11-trans Leukotriene D4(11-transLTD4) is a C-11 double bond isomer of LTD4. LTD4 undergoes slow temperature-dependent isomerization to 11-transLTD4 during storage. 11-transLTD4 retains about 10-25 % of the potency for contraction of guinea pig ileum, trachea and parenchyma compared to LTD4.1,2 It exhibits an ED50 ranging between 12-60 nM for contraction of guinea pig trachea.2,3 |
| 别名 | 11-transLTD4; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Baker, S.R.,Boot, J.R.,Jamieson, W.B., et al. The comparative in vitro pharmacology of leukotriene D4 and its isomers. Biochemical and Biophysical Research Communications 103(4), 1258-1264 (1981).
2.Tsai, B.S.,Bernstein, P.,Macia, R.A., et al. Comparative potency and pharmacology of isomers of leukotriene D4 on guinea-pig trachea: Requirement for a 5(S)6(R) configuration. Prostaglandins 23(4), 489-506 (1982).
3.Krell, R.D.,Osborn, R.,Falcone, K., et al. Contraction of isolated airway smooth muscle by synthetic leukotrienes C4 and D4. Prostaglandins 22(3), 387-409 (1981).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥97% |
| 计算分子量 | 496.7 |
| 分子式 | C25H40N2O6S |
| CAS号 | 79768-40-4 |
| 稳定性 | ≥ 1 year |
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