20-trifluoro Leukotriene B4
货号：
20195-100ug 基本售价：
6748.0 元 规格：
100 ug
产品信息
概述| 货号 | 20195-100ug |
| 描述 | 20-trifluoro LTB4 is a synthetic analog of LTB4 resistant to metabolism by ω-oxidation.1 It is equipotent to LTB4 in chemotactic activity with an EC50 of 3 nM.2,3 In contrast to its chemotactic activity, 20-trifluoro LTB4 inhibits LTB4 induced degranulation of neutrophils with an IC50 of 1-2 nM.2,3,1 |
| 别名 | 20-trifluoro LTB4; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Tanaka, Y.,Klauck, T.M.,Jubiz, W., et al. Biosynthesis of 20,20,20-trifluoroleukotriene B4 from 20,20,20-trifluoroarachidonic acid: A metabolically stable analog of leukotriene B4 and its application to a study of stimulation of leukotriene B4 synthesis by immunoglobulin G. Archives of Biochemistry and Biophysics 263, 178-190 (1988).
2.Tsai, B.S.,Keith, R.H.,Villani-Price, D., et al. Differential effects of 20-trifluoromethyl leukotriene B4 on human neutrophil functions. Prostaglandins 37, 287-302 (1989).
3.Nilssin, E.,Gyllenhammar, H.,Lerner, R., et al. The effect of 20-trifluoromethyl leukotriene B4 on neutrophil functional responses. Scandinavian Journal of Immunology 33, 357-363 (1991).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥97% |
| 计算分子量 | 390.4 |
| 分子式 | C20H29F3O4 |
| CAS号 | 115178-97-7 |
| 稳定性 | ≥ 1 year |
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