| 货号 | 64925-1mg |
| 描述 | The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.1,2PtdIns-(5)-P1 can be further phosphorylated to give diphosphates such as PtdIns-(4,5)-P2. These can also be cleaved by PI-specific phospholipase C (PLC) to give inositol triphosphates (IP3). The diacyl glycerol and IP3 generated by this PLC-cleavage are also part of a complex biochemical and signal transduction cascade which has not been entirely elucidated. For some additional reading, please see references 2,3,4. |
| 别名 | DPPI-5-P1; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Lapetina, E.G.,Billah, M.M., and Cuatrecasas, P. The phosphatidylinositol cycle and the regulation of arachidonic acid production. Nature 292, 367-369 (1981). 2.Majerus, P.W. Inositol phosphate biochemistry. Annual Reviews of Biochemistry 61, 225-250 (1992). 3.Pike, L.J., and Casey, L. Localization and turnover of phosphatidylinositol 4,5-bisphosphate in caveolin-enriched membrane domains. The Journal of Biological Chemisty 271, 26453-26456 (1996). 4.Berridge, M.J. Inositol trisphosphate and calcium signalling. Nature 361, 315-325 (1993). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 925.1 |
| 分子式 | C41H78O16P2 • 2NH4 |
| 稳定性 | ≥ 1 year |
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